tert-Butyl (R)-2-(aminomethyl)piperidine-1-carboxylate

tert-Butyl (R)-2-(aminomethyl)piperidine-1-carboxylate - Names and Identifiers

Name	tert-Butyl (2R)-2-(aminomethyl)piperidine-1-carboxylate
Synonyms	(R)-1-Boc-2-(aMinoMethyl)piperidine (R)-2-(Aminomethyl)-1-Boc-piperidine (R)-2-AMINOMETHYL-1-N-BOC-PIPERIDINE (2R)-2-(Aminomethyl)piperidine,N1-BOCprotected (R)-2-(Aminomethyl)-1-N-Boc-piperidine hydrochloride tert-Butyl (R)-2-(aminomethyl)piperidine-1-carboxylate (R)-TERT-BUTYL-2-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE tert-Butyl (2R)-2-(aminomethyl)piperidine-1-carboxylate (R)-2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-Piperidinecarboxylic acid, 2-(aminomethyl)-, 1,1-dimethylethyl ester, (2R)-
CAS	683233-14-9
InChI	InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13-7-5-4-6-9(13)8-12/h9H,4-8,12H2,1-3H3/t9-/m1/s1

tert-Butyl (R)-2-(aminomethyl)piperidine-1-carboxylate - Physico-chemical Properties

Molecular Formula	C11H22N2O2
Molar Mass	214.3
Density	1.023
Boling Point	299.4±13.0 °C(Predicted)
Flash Point	134.9°C
Vapor Presure	0.00119mmHg at 25°C
pKa	10.32±0.29(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.481

tert-Butyl (R)-2-(aminomethyl)piperidine-1-carboxylate - Introduction

tert-Butyl (2R)-2-(aminomethyl)piperidine-1-carboxylate is an organic compound. Its chemical formula is C13H25N3O2 and its molecular weight is 251.36g/mol.

Nature:
tert-Butyl (2R)-2-(aminomethyl)piperidine-1-carboxylate is a white solid with a low melting and boiling point. It is stable at room temperature and soluble in some organic solvents such as dichloromethane and ethanol.

Use:
tert-Butyl (2R)-2-(aminomethyl)piperidine-1-carboxylate are commonly used as intermediates in organic synthesis. Its amino methyl functional groups can participate in a variety of chemical reactions, resulting in the synthesis of a variety of drugs, chemicals and organic compounds.

Preparation Method:
tert-Butyl (2R)-2-(aminomethyl)piperidine-1-carboxylate can be synthesized in several steps. A common method is to first synthesize (R)-2-aminomethylpiperidine, which is then reacted with Boc acid chloride to produce the tert-Butyl (2R)-2-(aminomethyl)piperidine-1-carboxylate.

Safety Information:
tert-Butyl (2R)-2-(aminomethyl)piperidine-1-carboxylate is a chemical and should be handled with caution. Appropriate protective equipment, including lab gloves and goggles, is required during operation. It should be stored in a dry and cool place, away from fire and oxidizing agents, and avoid contact with strong acids or alkalis. When handling, avoid inhaling aerosols or dust, and take care to avoid skin and eye contact. If inadvertently exposed, should immediately rinse with plenty of water, and seek professional help.

Last Update：2024-04-09 15:17:59